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Boston University, Photonics Center, Boston, MA
Boston University, Photonics Center, Boston, MA
PhD Student (KABlab, Mesoscale Soft Matter Lab, PI: Dr. Keith Brown) https://www.kablab.org/
Sep. 2020 – Present
Research topic: Autonomous optimization for multifunctional polymer films
Funding sources: Division of Chemical, Bioengineering, Environmental, and Transport System (NSF), Toyota Research Institute, Boston University Dean's Catalyst Award (2020), U.S. Army Natick Soldier Systems Center
Highlights
Developed a self-driving lab (PANDA) for high-throughput polymer films deposition, integrating machine learning for optimization and uncertainty reduction in experimental parameter space.
Designed and fabricated custom hardware, including PDMS gaskets and a substrate holder, for precise polymer film deposition and characterization.
Applied advanced imaging techniques to assess film functionalization, homogeneity, and defects.
Collaborated with multidisciplinary teams to develop methodologies for thin film characterization and enhance deposition uniformity.
Optimized polymer synthesis conditions, including molecular weight, concentration, and crosslinking.
Implemented machine learning algorithms to refine experimental designs and improve data reproducibility.
Materials Characterization and Fabrication Techniques Used
Microscopy and Imaging:
Optical Microscopy
Scanning Electron Microscopy (SEM)
Spectroscopy and Analytical Techniques:
Ellipsometry
UV-Vis Spectroscopy and Assays
Electrochemical Fabrication:
Polymer film electrodeposition
Prototyping and Microfabrication:
3D Printing
CO2 Laser Cutting and Engraving
Electron Beam Lithography
Photolithography
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Thin Film Deposition:
Direct Current (DC) Sputtering
Electron Beam Evaporation (Physical Vapor Deposition)
Spin-coating
Publications
Quinn, H.; Robben, G. A.; Zheng, Z.; Gardner, A. L.; Werner, J. G.; Brown, K. A. PANDA: A Self-Driving Lab for Studying Electrodeposited Polymer Films. Mater. Horiz. 2024, 11, 5331-5340. https://doi.org/10.1039/D4MH00797B
Quinn, H.; Wang, W.; Werner, J. G.; Brown, K. A. Screening for Electrically Conductive Defects in Thin Functional Films Using Electrochemiluminescence. Anal. Methods 2023, 15 (29), 3592–3600. https://doi.org/10.1039/D3AY00687E.
Hershey Medical Center, Cancer Institute, Hershey, PA
Hershey Medical Center, Cancer Institute, Hershey, PA
Research Intern (Advisor: Dr. Raghu Sinha)
Jan. 2015 – Jun. 2015
Research topic: Targeted Delivery into the Nucleus of Live Cells - Using MB231 cell line and KI67 Antibody
Abstract: Digitonin, a glycoside that is frequently used as a detergent, was used to create temporary pores in the nucleus of MB231. This allowed the monoclonal antibody Ki-67 to enter the nucleus, where it bound to the Ki-67 marker protein. Previously, poration of the nucleus to allow antibodies to enter the nucleus required cell fixation, thereby killing the cells. This procedure allows live cells to be studied with target antibodies delivered to the nucleus.
Outcome: Presented poster at Biotechnology Summit in Harrisburg, PA (2015)
Harrisburg University, Harrisburg, PA
Harrisburg University, Harrisburg, PA
Research Assistant (Advisor: Dr. Leena Pattarkine)
Dec. 2013 – May 2015
Research topic: Herbal oil-based antimicrobial nanoparticles
Overview:
Confidential research funded by a personal care product company
Provided monthly status updates with data supporting recommendations for potential candidates
Outcome: Identified an improved alternative to the antimicrobial agent used by the company
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